Figure. Concentration-dependent activation of ADORA2B by NECA

Reporter cells were transfected with either the expression plasmid for human adenosine A2b receptor (ADORA2B) or the mock plasmid and treated with various concentrations of NECA. Data points shown are the mean ± SEM of an experiment (n = 3), and the curve is a fit to Hill equation with an EC50 of 19 nM.

adenosine A2b receptor
Available assay modes
Agonist, Inverse agonist, Antagonist, PAM, NAM
à la carte, Immunology/Infection, Human non-orphan GPCRs

ADORA2B orthologs in other animal species including rat, rabbit, dog, and macaque monkey are ready upon request.

Related Receptors