Description
Figure. Concentration-dependent activation of CALCRL by CGRP. Reporter cells were transfected with the expression plasmid for calcitonin receptor like receptor (CALCRL) and treated with various concentrations of calcitonin gene-related peptide (CGRP). Data points shown are the mean ± SEM of an experiment performed in triplicate, and the curve is a fit to Hill equation with an EC50 of 1.0 nM.