Figure. Concentration-dependent activation of CMKLR1 by chemerin. Reporter cells were transfected with the expression plasmid for chemerin chemo­kine-like receptor 1 (CMKLR1) and treated with various concentrations of chemerin. Data points shown are the mean ± SEM of an experiment performed in triplicate, and the curve is a fit to Hill equation with an EC50 of 15 nM.