Human CRHR2

Figure. Concentration-dependent activation of CRHR2 by urocortin

Reporter cells were transfected with either the expression plasmid for human corticotropin releasing hormone receptor 2 (CRHR2) or the mock plasmid and treated with various concentrations of urocortin. Data points shown are the mean ± SEM of an experiment (n = 3), and the curve is a fit to Hill equation with an EC50 of 23 nM.