Human DRD3

Figure. Concentration-dependent activation of DRD3 by dopamine

Reporter cells were transfected with either the expression plasmid for human dopamine receptor D3 (DRD3) or the mock plasmid and treated with various concentrations of dopamine. Data points shown are the mean ± SEM of an experiment (n = 3), and the curve is a fit to Hill equation with an EC50 of 220 nM.