GRM5

Assay services
Available
Assay modes
Agonist, Inverse agonist, Antagonist, PAM, NAM
HGNC symbol
GRM5
HGNC name
glutamate metabotropic receptor 5
Family
Metabotropic glutamate receptors
Species
Human
Guide to Pharmacology link
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=293

Description

Figure. Concentration-dependent activation of GRM5 by L-glutamic acid. Reporter cells were transfected with either the expression plasmid for glutamate metabo­tropic receptor 5 (GRM5) or the mock plasmid and treated with various concentrations of L-glutamic acid. Data points shown are the mean ± SEM of an experiment performed in triplicate, and the curve is a fit to Hill equation with an EC50 of 5.9 µM.