OPRK1

Assay services
Available
Assay modes
Agonist, Inverse agonist, Antagonist, PAM, NAM
HGNC symbol
OPRK1
HGNC name
opioid receptor kappa 1
Family
Opioid receptors
Species
Human
Guide to Pharmacology link
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=318
Contact Us

Description

Figure. Concentration-dependent activation of OPRK1 by dynorphin A. Reporter cells were transfected with either the expression plasmid for opi­oid receptor kappa 1 (OPRK1) or the mock plasmid and treated with various concentrations of dynorphin A. Data points shown are the mean ± SEM of an experiment performed in triplicate, and the curve is a fit to Hill equation with an EC50 of 8.2 nM.