Figure. Concentration-dependent activation of OPRL1 by noci­ceptin. Reporter cells were transfected with either the expression plasmid for opi­oid re­lated noci­ceptin receptor 1 (OPRL1) or the mock plasmid and treated with various concentrations of noci­ceptin. Data points shown are the mean ± SEM of an experiment performed in triplicate, and the curve is a fit to Hill equation with an EC50 of 290 pM.