HCRTR1

Figure. Concentration-dependent activation of HCRTR1 by orexin A
Reporter cells were transfected with either the expression plasmid for hypocretin receptor 1 (HCRTR1) or the mock plasmid and treated with various concentrations of orexin A. Data points shown are the mean ± SEM of an experiment, and the curve is a fit to Hill equation with an EC50 of 1.6 nM.
Assay modes
Agonist, Inverse agonist, Antagonist, PAM, NAM
Panels
Psychiatry, Non-orphan GPCRs
Symbol
HCRTR1
Nomenclature
hypocretin receptor 1
Family
Species
Human