HCRTR1

Assay services
Available
Assay modes
Agonist, Inverse agonist, Antagonist, PAM, NAM
HGNC symbol
HCRTR1
HGNC name
hypocretin receptor 1
Family
Orexin receptors
Species
Human
Guide to Pharmacology link
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=321
Contact Us

Description

Figure. Concentration-dependent activation of HCRTR1 by orexin A. Reporter cells were transfected with either the expression plasmid for hypo­cre­tin receptor 1 (HCRTR1) or the mock plasmid and treated with various concentrations of orexin A. Data points shown are the mean ± SEM of an experiment performed in triplicate, and the curve is a fit to Hill equation with an EC50 of 1.6 nM.