Figure. Concentration-dependent activation of PTH2R by PTH. Reporter cells were transfected with either the expression plasmid for par­a­thy­roid hormone 2 receptor (PTH2R) or the mock plasmid and treated with various concentrations of par­a­thy­roid hormone (PTH). Data points shown are the mean ± SEM of an experiment performed in triplicate, and the curve is a fit to Hill equation with an EC50 of 9.0 nM.