- G protein-coupled bile acid receptor 1
- Available assay modes
- Agonist, Inverse agonist, Antagonist, PAM, NAM
- à la carte, Gastrointestinal, Human non-orphan GPCRs
Figure. Concentration-dependent activation of GPBAR1 by TGR5 agonist
Reporter cells were transfected with either the expression plasmid for human G protein-coupled bile acid receptor 1 (GPBAR1) or the mock plasmid and treated with various concentrations of TGR5 agonist. Data points shown are the mean ± SEM of an experiment (n = 3), and the curve is a fit to Hill equation with an EC50 of 350 nM.