Figure. Concentration-dependent activation of NMBR by NMB. Reporter cells were transfected with either the expression plasmid for neuro­medin B receptor (NMBR) or the mock plasmid and treated with various concentrations of neuro­medin B (NMB). Data points shown are the mean ± SEM of an experiment performed in triplicate, and the curve is a fit to Hill equation with an EC50 of 590 pM.