MTNR1B

Assay services
Available
Assay modes
Agonist, Inverse agonist, Antagonist, PAM, NAM
HGNC symbol
MTNR1B
HGNC name
melatonin receptor 1B
Family
Melatonin receptors
Species
Human
Guide to Pharmacology link
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=288
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Description

Figure. Concentration-dependent activation of MTNR1B by melato­nin. Reporter cells were transfected with either the expression plasmid for melato­nin receptor 1B (MTNR1B) or the mock plasmid and treated with various concentrations of melato­nin. Data points shown are the mean ± SEM of an experiment performed in triplicate, and the curve is a fit to Hill equation with an EC50 of 95 pM.