Human MTNR1B

Figure. Concentration-dependent activation of MTNR1B by melatonin

Reporter cells were transfected with either the expression plasmid for human melatonin receptor 1B (MTNR1B) or the mock plasmid and treated with various concentrations of melatonin. Data points shown are the mean ± SEM of an experiment (n = 3), and the curve is a fit to Hill equation with an EC50 of 95 pM.