GRM4

Assay services
Available
Assay modes
Agonist, Inverse agonist, Antagonist, PAM, NAM
HGNC symbol
GRM4
HGNC name
glutamate metabotropic receptor 4
Family
Metabotropic glutamate receptors
Species
Human
Guide to Pharmacology link
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=292
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Description

Figure. Concentration-dependent activation of GRM4 by L-glutamic acid. Reporter cells were transfected with either the expression plasmid for glutamate metabo­tropic receptor 4 (GRM4) or the mock plasmid and treated with various concentrations of L-glutamic acid. Data points shown are the mean ± SEM of an experiment performed in triplicate, and the curve is a fit to Hill equation with an EC50 of 34 µM.