Mouse Gpr35

Figure. Concentration-dependent activation of Gpr35 by zaprinast

Reporter cells were transfected with either the expression plasmid for mouse G protein-coupled receptor 35 (Gpr35) or the mock plasmid and treated with various concentrations of zaprinast. Data points shown are the mean ± SEM of an experiment (n = 3), and the curve is a fit to Hill equation with an EC50 of 700 nM.