Figure. Concentration-dependent activation of CCKAR by CCK‐8

Reporter cells were transfected with either the expression plasmid for human cholecystokinin A receptor (CCKAR) or the mock plasmid and treated with various concentrations of CCK‐8. Data points shown are the mean ± SEM of an experiment (n = 3), and the curve is a fit to Hill equation with an EC50 of 17 nM.

cholecystokinin A receptor
Available assay modes
Agonist, Inverse agonist, Antagonist, PAM, NAM
à la carte, Oncology, Endocrinology/Metabolism, Psychiatry, Gastrointestinal, Human non-orphan GPCRs

CCKAR orthologs in other animal species including rat, rabbit, dog, and macaque monkey are ready upon request.

Related Receptors