Figure. Concentration-dependent activation of CCKBR by CCK‐8

Reporter cells were transfected with either the expression plasmid for human cholecystokinin B receptor (CCKBR) or the mock plasmid and treated with various concentrations of CCK‐8. Data points shown are the mean ± SEM of an experiment (n = 3), and the curve is a fit to Hill equation with an EC50 of 490 pM.

cholecystokinin B receptor
Available assay modes
Agonist, Inverse agonist, Antagonist, PAM, NAM
à la carte, Oncology, Endocrinology/Metabolism, Psychiatry, Neurology, Gastrointestinal, Human non-orphan GPCRs

CCKBR orthologs in other animal species including rat, rabbit, dog, and macaque monkey are ready upon request.

Related Receptors

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