EDNRA

Assay services
Available
Assay modes
Agonist, Inverse agonist, Antagonist, PAM, NAM
HGNC symbol
EDNRA
HGNC name
endothelin receptor type A
Family
Endothelin receptors
Species
Human
Guide to Pharmacology link
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=219

Description

Figure. Concentration-dependent activation of EDNRA by ET-1. Reporter cells were transfected with either the expression plasmid for endo­thelin receptor type A (EDNRA) or the mock plasmid and treated with various concentrations of endo­thelin 1 (ET-1). Data points shown are the mean ± SEM of an experiment performed in triplicate, and the curve is a fit to Hill equation with an EC50 of 5.5 nM.