Human GCGR

Figure. Concentration-dependent activation of GCGR by glucagon

Reporter cells were transfected with either the expression plasmid for human glucagon receptor (GCGR) or the mock plasmid and treated with various concentrations of glucagon. Data points shown are the mean ± SEM of an experiment (n = 3), and the curve is a fit to Hill equation with an EC50 of 6.3 nM.