HCAR3

Assay services
Available
Assay modes
Agonist, Inverse agonist, Antagonist, PAM, NAM
HGNC symbol
HCAR3
HGNC name
hydroxycarboxylic acid receptor 3
Family
Hydroxycarboxylic acid receptors
Species
Human
Guide to Pharmacology link
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=313

Description

Figure. Concentration-dependent activation of HCAR3 by 3-OH-octanoic acid. Reporter cells were transfected with the expression plasmid for hy­drox­­ycar­box­ylic acid receptor 3 (HCAR3) and treated with various concentrations of 3-OH-octanoic acid. Data points shown are the mean ± SEM of an experiment performed in triplicate, and the curve is a fit to Hill equation with an EC50 of 130 µM.