Description
Figure. Concentration-dependent activation of HCAR3 by 3-OH-octanoic acid. Reporter cells were transfected with the expression plasmid for hydroxycarboxylic acid receptor 3 (HCAR3) and treated with various concentrations of 3-OH-octanoic acid. Data points shown are the mean ± SEM of an experiment performed in triplicate, and the curve is a fit to Hill equation with an EC50 of 130 µM.