S1PR3

Assay services
Available
Assay modes
Agonist, Inverse agonist, Antagonist, PAM, NAM
HGNC symbol
S1PR3
HGNC name
sphingosine-1-phosphate receptor 3
Family
Lysophospholipid (S1P) receptors
Species
Human
Guide to Pharmacology link
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=277

Description

Figure. Concentration-dependent activation of S1PR3 by S1P. Reporter cells were transfected with either the expression plasmid for sphin­go­sine-1-phos­phate receptor 3 (S1PR3) or the mock plasmid and treated with various concentrations of sphin­go­sine 1-phos­phate (S1P). Data points shown are the mean ± SEM of an experiment performed in triplicate, and the curve is a fit to Hill equation with an EC50 of 23 nM.