Human MC2R

Figure. Concentration-dependent activation of MC2R by ACTH

Reporter cells were transfected with either the expression plasmid for human melanocortin 2 receptor (MC2R) or the mock plasmid and treated with various concentrations of ACTH. Data points shown are the mean ± SEM of an experiment (n = 3), and the curve is a fit to Hill equation with an EC50 of 4.1 nM.

説明

Nomenclature: melanocortin 2 receptor
Available assay modes: Agonist, Inverse agonist, Antagonist, PAM, NAM
Panels: à la carte, Immunology/Infection, Endocrinology/Metabolism, Musculoskeletal, Urology/Reproduction, Human non-orphan GPCRs

MC2R orthologs in other animal species including rat, rabbit, dog, and macaque monkey are ready upon request.

Related Receptors


Human	MC1R melanocortin 1 receptor
Human	MC2R melanocortin 2 receptor
Human	MC3R melanocortin 3 receptor
Human	MC4R melanocortin 4 receptor
Human	MC5R melanocortin 5 receptor
Mouse	Mc1r melanocortin 1 receptor
Mouse	Mc2r melanocortin 2 receptor
Mouse	Mc3r melanocortin 3 receptor
Mouse	Mc4r melanocortin 4 receptor
Mouse	Mc5r melanocortin 5 receptor

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