MC2R

Assay services
Available
Assay modes
Agonist, Inverse agonist, Antagonist, PAM, NAM
HGNC symbol
MC2R
HGNC name
melanocortin 2 receptor
Family
Melanocortin receptors
Species
Human
Guide to Pharmacology link
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=283
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Description

Figure. Concentration-dependent activation of MC2R by ACTH. Reporter cells were transfected with either the expression plasmids for melano­cortin 2 receptor (MC2R) and the MC2R accessory protein (MRAP) or the mock plasmid and treated with various concentrations of adreno­cortico­tropic hormone (ACTH). Data points shown are the mean ± SEM of an experiment performed in triplicate, and the curve is a fit to Hill equation with an EC50 of 4.1 nM.