Human MC4R

Figure. Concentration-dependent activation of MC4R by α‐MSH

Reporter cells were transfected with either the expression plasmid for human melanocortin 4 receptor (MC4R) or the mock plasmid and treated with various concentrations of α‐MSH. Data points shown are the mean ± SEM of an experiment (n = 3), and the curve is a fit to Hill equation with an EC50 of 600 pM.

melanocortin 4 receptor
Available assay modes
à la carte | Endocrinology/Metabolism | Human non-orphan GPCRs

MC4R orthologs in other animal species including rat, rabbit, dog, and macaque monkey are ready upon request.

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