Human CHRM1

Figure. Concentration-dependent activation of CHRM1 by carbachol

Reporter cells were transfected with either the expression plasmid for human cholinergic receptor muscarinic 1 (CHRM1) or the mock plasmid and treated with various concentrations of carbachol. Data points shown are the mean ± SEM of an experiment (n = 3), and the curve is a fit to Hill equation with an EC50 of 310 nM.

Nomenclature
cholinergic receptor muscarinic 1
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CHRM1 orthologs in other animal species including rat, rabbit, dog, and macaque monkey are ready upon request.

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