Mouse Avpr1b

Figure. Concentration-dependent activation of Avpr1b by [R]‐vasopressin

Reporter cells were transfected with either the expression plasmid for mouse arginine vasopressin receptor 1B (Avpr1b) or the mock plasmid and treated with various concentrations of the reference agonist. Data points shown are the mean ± SEM of an experiment (n = 4).

arginine vasopressin receptor 1B
Available assay modes
Agonist, Inverse agonist, Antagonist, PAM, NAM
à la carte, Mouse non-orphan GPCRs

Vasopressin and oxytocin receptors

Vasopressin (AVP) and oxytocin (OT) receptors are activated by the endogenous cyclic nonapeptides vasopressin and oxytocin. These peptides are derived from precursors which also produce neurophysins (neurophysin I for oxytocin; neurophysin II for vasopressin). Vasopressin and oxytocin differ at only 2 amino acids (positions 3 and 8). There are metabolites of these neuropeptides that may be biologically active [1].


  1. de Wied D, Diamant M, Fodor M. Central nervous system effects of the neurohypophyseal hormones and related peptides. Front Neuroendocrinol 1993;14:251-302.
Excerpt from IUPHAR/BPS Guide to Pharmacology

Related Receptors

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