We have all the 313 human non-sensory GPCRs in native sequences and provide functional assay for them in a single format, regardless of the subtypes of Gα proteins coupled. Click below for details.

Family
Panel
Filters Sort results
Reset Apply
Receptor
Family
Species
Assays
Human
Available
Assay modes:
Agonist
Inverse agonist
Antagonist
PAM
NAM
Panels:
Psychiatry
Neurology
Gastrointestinal
Non-orphan GPCRs
Reference agonist:
serotonin
EC50:
13 nM
Human
Available
Assay modes:
Agonist
Inverse agonist
Antagonist
PAM
NAM
Panels:
Psychiatry
Neurology
Cardiology
Non-orphan GPCRs
Reference agonist:
serotonin
EC50:
4.0 nM
Human
Available
Assay modes:
Agonist
Inverse agonist
Antagonist
PAM
NAM
Panels:
Non-orphan GPCRs
Reference agonist:
serotonin
EC50:
2.7 nM
Human
Available
Assay modes:
Agonist
Inverse agonist
Antagonist
PAM
NAM
Panels:
Non-orphan GPCRs
Reference agonist:
serotonin
EC50:
3.2 nM
Human
Available
Assay modes:
Agonist
Inverse agonist
Antagonist
PAM
NAM
Panels:
Non-orphan GPCRs
Reference agonist:
serotonin
EC50:
3.3 nM
Human
Available
Assay modes:
Agonist
Inverse agonist
Antagonist
PAM
NAM
Panels:
Endocrinology/Metabolism
Psychiatry
Neurology
Respiratory
Non-orphan GPCRs
Reference agonist:
serotonin
EC50:
1.9 nM
Human
Available
Assay modes:
Agonist
Inverse agonist
Antagonist
PAM
NAM
Panels:
Cardiology
Respiratory
Non-orphan GPCRs
Reference agonist:
serotonin
EC50:
2.5 nM
Human
Available
Assay modes:
Agonist
Inverse agonist
Antagonist
PAM
NAM
Panels:
Endocrinology/Metabolism
Psychiatry
Neurology
Non-orphan GPCRs
Reference agonist:
serotonin
EC50:
1.7 nM
Human
Available
Assay modes:
Agonist
Inverse agonist
Antagonist
PAM
NAM
Panels:
Cardiology
Non-orphan GPCRs
Reference agonist:
serotonin
EC50:
26 nM
Human
Available
Assay modes:
Agonist
Inverse agonist
Antagonist
PAM
NAM
Panels:
Psychiatry
Non-orphan GPCRs
Reference agonist:
serotonin
EC50:
85 nM
Human
Available
Assay modes:
Agonist
Inverse agonist
Antagonist
PAM
NAM
Panels:
Psychiatry
Non-orphan GPCRs
Reference agonist:
serotonin
EC50:
8.6 nM
Human
Available
Assay modes:
Agonist
Inverse agonist
Antagonist
PAM
NAM
Panels:
Psychiatry
Neurology
Musculoskeletal
Non-orphan GPCRs
Reference agonist:
serotonin
EC50:
1.8 nM
Human
Available
Assay modes:
Agonist
Inverse agonist
Antagonist
PAM
NAM
Panels:
Psychiatry
Neurology
Non-orphan GPCRs
Reference agonist:
carbachol
EC50:
310 nM
Human
Available
Assay modes:
Agonist
Inverse agonist
Antagonist
PAM
NAM
Panels:
Immunology/Infection
Endocrinology/Metabolism
Psychiatry
Neurology
Urology/Reproduction
Non-orphan GPCRs
Reference agonist:
carbachol
EC50:
110 nM
Human
Available
Assay modes:
Agonist
Inverse agonist
Antagonist
PAM
NAM
Panels:
Immunology/Infection
Hematology
Endocrinology/Metabolism
Psychiatry
Ophthalmology
Cardiology
Respiratory
Gastrointestinal
Dermatology
Musculoskeletal
Urology/Reproduction
Non-orphan GPCRs
Reference agonist:
carbachol
EC50:
31 nM
Human
Available
Assay modes:
Agonist
Inverse agonist
Antagonist
PAM
NAM
Panels:
Psychiatry
Neurology
Non-orphan GPCRs
Reference agonist:
carbachol
EC50:
47 nM
Human
Available
Assay modes:
Agonist
Inverse agonist
Antagonist
PAM
NAM
Panels:
Psychiatry
Non-orphan GPCRs
Reference agonist:
carbachol
EC50:
5.9 nM
Human
Available
Assay modes:
Agonist
Inverse agonist
Antagonist
PAM
NAM
Panels:
Neurology
Cardiology
Respiratory
Non-orphan GPCRs
Reference agonist:
NECA
EC50:
4.8 nM
Human
Available
Assay modes:
Agonist
Inverse agonist
Antagonist
PAM
NAM
Panels:
Immunology/Infection
Psychiatry
Neurology
Ophthalmology
Cardiology
Respiratory
Dermatology
Musculoskeletal
Non-orphan GPCRs
Reference agonist:
NECA
EC50:
11 nM
Human
Available
Assay modes:
Agonist
Inverse agonist
Antagonist
PAM
NAM
Panels:
Immunology/Infection
Non-orphan GPCRs
Reference agonist:
NECA
EC50:
19 nM
Human
Available
Assay modes:
Agonist
Inverse agonist
Antagonist
PAM
NAM
Panels:
Gastrointestinal
Non-orphan GPCRs
Reference agonist:
NECA
EC50:
1.6 nM
Human
Available
Assay modes:
Agonist
Inverse agonist
Antagonist
PAM
NAM
Panels:
Immunology/Infection
Oncology
Hematology
Endocrinology/Metabolism
Ophthalmology
Cardiology
Respiratory
Gastrointestinal
Dermatology
Urology/Reproduction
Non-orphan GPCRs
Reference agonist:
L-phenylephrine
EC50:
18 nM
Human
Available
Assay modes:
Agonist
Inverse agonist
Antagonist
PAM
NAM
Panels:
Neurology
Cardiology
Non-orphan GPCRs
Reference agonist:
L-phenylephrine
EC50:
28 nM
Human
Available
Assay modes:
Agonist
Inverse agonist
Antagonist
PAM
NAM
Panels:
Non-orphan GPCRs
Reference agonist:
L-phenylephrine
EC50:
67 nM
Human
Available
Assay modes:
Agonist
Inverse agonist
Antagonist
PAM
NAM
Panels:
Psychiatry
Cardiology
Dermatology
Musculoskeletal
Non-orphan GPCRs
Reference agonist:
noradrenaline
EC50:
71 nM
Human
Available
Assay modes:
Agonist
Inverse agonist
Antagonist
PAM
NAM
Panels:
Immunology/Infection
Oncology
Hematology
Psychiatry
Neurology
Ophthalmology
Cardiology
Respiratory
Gastrointestinal
Dermatology
Urology/Reproduction
Non-orphan GPCRs
Reference agonist:
noradrenaline
EC50:
33 nM
Human
Available
Assay modes:
Agonist
Inverse agonist
Antagonist
PAM
NAM
Panels:
Cardiology
Non-orphan GPCRs
Reference agonist:
noradrenaline
EC50:
89 nM
Human
Available
Assay modes:
Agonist
Inverse agonist
Antagonist
PAM
NAM
Panels:
Endocrinology/Metabolism
Psychiatry
Cardiology
Gastrointestinal
Non-orphan GPCRs
Reference agonist:
isoproterenol
EC50:
22 nM
Human
Available
Assay modes:
Agonist
Inverse agonist
Antagonist
PAM
NAM
Panels:
Immunology/Infection
Oncology
Hematology
Endocrinology/Metabolism
Psychiatry
Neurology
Ophthalmology
Cardiology
Respiratory
Gastrointestinal
Dermatology
Musculoskeletal
Urology/Reproduction
Non-orphan GPCRs
Reference agonist:
isoproterenol
EC50:
26 nM
Human
Available
Assay modes:
Agonist
Inverse agonist
Antagonist
PAM
NAM
Panels:
Endocrinology/Metabolism
Cardiology
Non-orphan GPCRs
Reference agonist:
isoproterenol
EC50:
47 nM
Human
Available
Assay modes:
Agonist
Inverse agonist
Antagonist
PAM
NAM
Panels:
Immunology/Infection
Oncology
Hematology
Endocrinology/Metabolism
Ophthalmology
Cardiology
Respiratory
Gastrointestinal
Dermatology
Musculoskeletal
Urology/Reproduction
Non-orphan GPCRs
AGTR1
Reference agonist:
angiotensin II
EC50:
920 pM
Human
Available
Assay modes:
Agonist
Inverse agonist
Antagonist
PAM
NAM
Panels:
Cardiology
Non-orphan GPCRs
Reference agonist:
apelin-13
EC50:
8.1 nM
Human
Available
Assay modes:
Agonist
Inverse agonist
Antagonist
PAM
NAM
Panels:
Gastrointestinal
Non-orphan GPCRs
Reference agonist:
TGR5 agonist
EC50:
350 nM
Human
Available
Assay modes:
Agonist
Inverse agonist
Antagonist
PAM
NAM
Panels:
Immunology/Infection
Oncology
Hematology
Endocrinology/Metabolism
Ophthalmology
Respiratory
Dermatology
Urology/Reproduction
Non-orphan GPCRs
Reference agonist:
bombesin
EC50:
2.4 nM
Human
Available
Assay modes:
Agonist
Inverse agonist
Antagonist
PAM
NAM
Panels:
Oncology
Psychiatry
Urology/Reproduction
Non-orphan GPCRs
Reference agonist:
GRP
EC50:
1.3 nM
Human
Available
Assay modes:
Agonist
Inverse agonist
Antagonist
PAM
NAM
Panels:
Oncology
Dermatology
Non-orphan GPCRs
Reference agonist:
NMB
EC50:
590 pM
Human
Available
Assay modes:
Agonist
Inverse agonist
Antagonist
PAM
NAM
Panels:
Immunology/Infection
Oncology
Hematology
Endocrinology/Metabolism
Ophthalmology
Cardiology
Respiratory
Gastrointestinal
Musculoskeletal
Urology/Reproduction
Non-orphan GPCRs
Reference agonist:
calcitonin
EC50:
2.7 nM
Human
Available
Assay modes:
Agonist
Inverse agonist
Antagonist
PAM
NAM
Panels:
Non-orphan GPCRs
Reference agonist:
CGRP
EC50:
1.0 nM
Human
Available
Assay modes:
Agonist
Inverse agonist
Antagonist
PAM
NAM
Panels:
Immunology/Infection
Oncology
Hematology
Endocrinology/Metabolism
Ophthalmology
Cardiology
Respiratory
Gastrointestinal
Dermatology
Musculoskeletal
Urology/Reproduction
Non-orphan GPCRs
Reference agonist:
cinacalcet
EC50:
140 nM
Human
Available
Assay modes:
Agonist
Inverse agonist
Antagonist
PAM
NAM
Panels:
Immunology/Infection
Oncology
Hematology
Endocrinology/Metabolism
Psychiatry
Neurology
Ophthalmology
Cardiology
Gastrointestinal
Dermatology
Musculoskeletal
Urology/Reproduction
Non-orphan GPCRs
Reference agonist:
Δ9-THC
EC50:
4.1 nM
Human
Available
Assay modes:
Agonist
Inverse agonist
Antagonist
PAM
NAM
Panels:
Reference agonist:
Δ9-THC
EC50:
11 nM
Human
Available
Assay modes:
Agonist
Inverse agonist
Antagonist
PAM
NAM
Panels:
Non-orphan GPCRs
Reference agonist:
LPI
EC50:
1.2 µM
Human
Available
Assay modes:
Agonist
Inverse agonist
Antagonist
PAM
NAM
Panels:
Non-orphan GPCRs
Reference agonist:
N-oleoylethanolamine
EC50:
6.3 µM
Human
Available
Assay modes:
Agonist
Inverse agonist
Antagonist
PAM
NAM
Panels:
Urology/Reproduction
Non-orphan GPCRs
Reference agonist:
chemerin
EC50:
15 nM
Human
Available
Assay modes:
Agonist
Inverse agonist
Antagonist
PAM
NAM
Panels:
Immunology/Infection
Hematology
Neurology
Ophthalmology
Cardiology
Respiratory
Gastrointestinal
Dermatology
Musculoskeletal
Non-orphan GPCRs
Reference agonist:
CCL3
EC50:
250 pM
Human
Available
Assay modes:
Agonist
Inverse agonist
Antagonist
PAM
NAM
Panels:
Immunology/Infection
Oncology
Hematology
Neurology
Ophthalmology
Cardiology
Respiratory
Gastrointestinal
Dermatology
Musculoskeletal
Urology/Reproduction
Non-orphan GPCRs
Reference agonist:
CCL2
EC50:
1.3 nM
Human
Available
Assay modes:
Agonist
Inverse agonist
Antagonist
PAM
NAM
Panels:
Immunology/Infection
Oncology
Hematology
Respiratory
Gastrointestinal
Dermatology
Non-orphan GPCRs
Reference agonist:
CCL22
EC50:
20 nM
Human
Available
Assay modes:
Agonist
Inverse agonist
Antagonist
PAM
NAM
Panels:
Immunology/Infection
Oncology
Hematology
Endocrinology/Metabolism
Neurology
Ophthalmology
Cardiology
Respiratory
Gastrointestinal
Dermatology
Musculoskeletal
Urology/Reproduction
Non-orphan GPCRs
Reference agonist:
CCL4
EC50:
7.1 nM
Human
Available
Assay modes:
Agonist
Inverse agonist
Antagonist
PAM
NAM
Panels:
Immunology/Infection
Oncology
Hematology
Ophthalmology
Cardiology
Respiratory
Gastrointestinal
Dermatology
Musculoskeletal
Urology/Reproduction
Non-orphan GPCRs
Reference agonist:
CCL20
EC50:
3.8 nM
Human
Available
Assay modes:
Agonist
Inverse agonist
Antagonist
PAM
NAM
Panels:
Immunology/Infection
Oncology
Hematology
Neurology
Ophthalmology
Gastrointestinal
Dermatology
Musculoskeletal
Non-orphan GPCRs
Reference agonist:
CCL21
EC50:
15 nM
1 2 7

Contact Us

Send us a message via the form below or write to us at [email protected].

Ordering Process

Service flow chart

Request a quotation

We hear about the study outline and propose experiments. A non-disclosure agreement is optional.

STEP
1

Place an order

You also ship your compounds to our lab and pay the fee via bank transfer.

STEP
2

Wait for a while

The turnaround time may be as short as two weeks but depends on the study scale and design and the backlog of orders.

STEP
3

Receive the report

We provide the study report via email.

STEP
4

Inquiry & RFQ Form